Imaging pattern and histological features of Gorham-Stout Disease of the radius

Mandibular Gorham–Stout disease

RATIONALE Gorham-Stout disease (GSD) is characterized by aggressive bone resorption, proliferation of vascular or lymphatic vessels, and soft-tissue swelling. Bones that initially appear normal start to resorb, partially or completely. However, the etiology of GSD is unknown. PATIENT CONCERNS A 29-year-old man with a chief complaint of toothache and mobility in the lower right mandible for th...

[The malignant degeneration of Gorham-Stout disease?].

Gorham-Stout Disease Management during Pregnancy

Gorham-Stout Disease (GSD) is a rare lymphatic disorder affecting children or young adults with no predilection of sex. It is generally associated with vanishing bone osteolytic lesions, thoracic and abdominal involvement, and diffuse pulmonary lymphangiomatosis. Chylous effusions and chylothorax, consequent to the abnormal proliferation of lymphatic vessels, may induce respiratory failure with...

Gorham-Stout Disease of the Shoulder: Clinical, Pathologic and Therapeutic Considerations

Background: Gorham-Stout disease (GSD) is a rare skeletal disorder characterized by massive osteolysis of a bony area in the body. When it hits the shoulder, the patient is faced with a debilitating limitation in terms of motion, stability and quality of life. GSD etiology and pathology are unknown and, as a result, therapeutic modalities remain unclear. The aim of this paper is to explore and ...

Gorham-Stout syndrome of the shoulder

INTRODUCTION Gorham-Stout syndrome (GSS) is a rare but severe subtype of idiopathic osteolysis. There are no guidelines for the treatment of GSS. We analysed different diagnostic and therapeutic regimes and we describe the sucessful treatment of GSS considering individual patient factors. METHODS We diagnosed three patients with shoulder-specific GSS using clinical, radiological and histopath...